Hypnotic Activity of Melatonin

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Hypnotic activity of melatonin: involvement of semicarbazide hydrochloride, blocker of synthetic enzyme for GABA.

AIM To assess the effect of semicarbazide hydrochloride (SCZ), the blocker of synthetic enzyme for GABA, on the hypnotic activity of melatonin. METHODS Righting reflex method in mice and electroencephalography (EEG) in rats were used to determine effects of SCZ on sleep and hypnotic activity of melatonin. RESULTS Melatonin displayed a marked hypnotic activity both in righting reflex experim...

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comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

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ژورنال

عنوان ژورنال: Sleep

سال: 2000

ISSN: 1550-9109,0161-8105

DOI: 10.1093/sleep/23.5.1i